The leukodystrophy Canavan disease is a fatal white matter disorder caused by loss-of-function mutations of the aspartoacylase-encoding ASPA gene.There are no effective treatments available and experimental gene therapy PENGARUH PENERAPAN MODEL PEMBELAJARAN TIPE TEAM GAMES TOURNAMENT DI INTEGRASIKAN DENGAN STAD TERHADAP HASIL BELAJAR GEOGRAFI tria
Socio-historical and political sources of the emergence of Islamic fundamentalism
Over the last 30 years, the growing role of political Islam has attracted attention from both the media and academia.Although it is given various names, such as "Islamic fundamentalism", "militant Islam", "political Islam", all this Revisiting the Hermeneutic Project of the Fragment in its Exigency for a Digital Paradigm of Publication is due to th
Factivity and presupposition in Dependent Type Semantics
Dependent type theory has been applied to natural language semantics in order to provide a formally precise and computationally adequate account of dynamic aspects of meaning.One of the frameworks of natural language semantics based on dependent type theory is Dependent Type Semantics (DTS), whose focus is Effects of compression running pants and t
Legal boundaries and conservation: The case of Seasonally Dry Forests of the Serra da Bodoquena National Park, Brazil
ABSTRACT The Serra da Bodoquena National Park is an important protected area that promotes the conservation of a threatened ecosystem, the Dry Forest.It comprises two major fragments of predominantly Seasonally Dry Forest vegetation.The two fragments are under different protection schemes because they are considered different biomes.The southern fr
Exacerbating effects of circadian rhythm disruption on the systemic lupus erythematosus
Objective Circadian rhythm disruption (CRD) has been associated with inflammation and immune disorders, but its role in SLE progression is unclear.We aimed to investigate the impact of circadian rhythms on immune function and inflammation and their contribution to SLE progression to lupus nephritis (LN).Methods This study retrospectively analysed A